Update: First patients dosed with COVID-19 nanovaccine in Phase 1 trial

Nanovaccine in clinical trial Phase 1

Moderna (MA, USA) has developed a mRNA vaccine – mRNA-1273 – for use against SARS-CoV-2, which is currently undergoing clinical trials in the USA.

The vaccine is made up of mRNAs encoding antigenic viral full-length S, S1 or S2 proteins from SARS-CoV and MERS-CoV virus strains and encapsulated in cationic lipid nanoparticles for more efficient delivery.

Now, Moderna has announced that the first patients have been dosed with the vaccine as part of the Phase 1 trial.

See the timeline of the vaccine’s development here: Timeline of response from Moderna.

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