DNA origami: the nanoscale tool for anticancer drug delivery

DNA origami peptoid coated for drug delivery

A collaborative research group has designed a chain of molecules, – peptoids – which, due to their particular length and sequence, are able to provide protection to 3D DNA origami nanostructures against structural degradation under biological conditions. The peptoid-coated DNA origami could be used to deliver anticancer drugs, proteins and biological molecules and targets cell surface receptors that have been implicated in cancer. DNA origami involves the folding of long DNA chains into different shapes at the nanoscale level. This is achieved with the pinning of different sections of the chain by their complementary base pairs in the short DNA...

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