Using nanomethods to deliver drugs for the treatment of cancer has been a focus for many cancer research groups in recent years. The use of nanoparticles and nanotechnology can enable the circumvention of many challenges that cancer therapies currently face. Nanotherapeutics can increase the stability, bioavailability and solubility of certain drugs, help them to cross barriers and direct them to targeted treatment sites. These benefits could help to reduce harmful side effects in patients and increase the efficiacy of current therapeutics when used as a vehicle or in combination. In this In Focus, The Nanomed Zone hopes to highlight how nanotechnology can be used to enhance cancer therapy through improved drug delivery.