HIV vaccine optimized using DNA origami

Written by Lucy Chard, Editor

HIV vaccine antigen specific DNA origami

Researchers from the Massachusetts Institute of Technology (MIT; MA, USA) have used DNA particles to design HIV-like particles using a DNA origami technique, which could be used as a HIV vaccine in the future. As DNA is a highly programmable molecule, scientists are able to manipulate it in a technique termed ‘DNA origami’ to develop molecules that can be used for applications such as drug delivery. In this instance, the team from MIT have taken DNA particles, which mimic the size and shape of viruses, and coated them with HIV-specific antigens to elicit an immune response. The precise control the...

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