Peek behind the paper: using nanoparticle ‘pseudo-virions’ to screen for potential COVID-19 therapeutics

Written by Kirill Gorshkov (National Center for Advancing Translational Sciences)

In this behind-the-paper interview, Kirill Gorshkov (National Center for Advancing Translational Sciences; NCATS, MD, USA) discusses recent research he was involved in utilizing a nanoparticle probe – in the form of a quantum dot conjugated to the receptor-binding domain of the SARS-CoV-2 spike protein – to visualize the interaction between the viral spike and the ACE2 protein, as well as how the system could be used to screen libraries for potential drug candidates for COVID-19 that inhibit this interaction. Read the full research paper here >>> Please can you introduce yourself and give a short summary of your research career...

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